2022 CPIP-D Case 4: Transfusion Medicine – Panagglutination: A Blood Bank’s Dilemma - CPIP0404W.2022
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Learn common causes of panagglutination and identify strategies to distinguish between causes of panagglutination in the hospital laboratory or reference laboratory.

Credit Type: CME
Duration: 1 hour 15 minutes
Launch Date: April 18, 2022
Expiration Date: April 17, 2025 11:59 PM (CT)
Pricing: Junior Member Fee: $10.00
MOC Category: Medical Knowledge, Patient Care

Registration Information
THIS ACTIVITY REQUIRES CREDIT CARD PAYMENT. If you ordered this product in advance, click Learning Search to locate the activity.

To enroll in the series with one easy payment, or to enroll multiple participants from the same institution, call 800-323-4040 option 1. This option is only available until December 31, 2022, after this date this activity is only accessible by an online credit card payment.

In pretransfusion testing, the antibody screen and panel may show a panagglutination pattern due to a variety of causes. Most panagglutinins are benign and do not cause hemolysis in vivo when patients are transfused. However, it is critical for blood banks to determine the cause of panagglutination to ensure safe and timely transfusion of these patients. Explore strategies for distinguishing key causes of panagglutination and implications for safely transfusing patients with panagglutination.

This clinical pathology activity is intended for pathologists.

After completing this activity, you should be able to:

  1. List the advantages and disadvantages of tube, gel (column agglutination), and solid-phase red cell adherence methodologies for antibody evaluation.
  2. Select the appropriate tests to determine the etiology of panagglutination.
  3. Create a blood bank protocol to manage patients with panagglutination due to monoclonal anti-CD38 therapy.

Alexis R. Peedin, MD, FCAP

Related Link
Clinical Pathology Improvement Program

CME Information
Accreditation: The College of American Pathologists (CAP) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

CME Category 1: The College of American Pathologists designates this internet enduring material educational activity for a maximum of 1.25 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Payment Information
To pay with a check, print a copy of this page and send it with your check to the address below. You will be notified when your payment has been processed and you have been registered into the activity.

College of American Pathologists
CAP Learning
325 Waukegan Road
Northfield, IL 60093-2750

Refund Policy
Refunds will be handled on an exception basis. Please submit your request to the CAP in writing via email at education@cap.org or fax at 847-832-8006.

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The CAP recognizes that some Veteran’s Administration, US Government, and military participants may have difficulty accessing the online activity. If you experience difficulty or have any questions, please contact a representative of the Customer Contact Center at 800-323-4040 option 1 or education@cap.org.

This activity and evaluation are available April 18, 2022, and expire April 17, 2025, at 11:59 PM (CT). Upon completion of the activity your credit will be awarded. Your certificate may be downloaded from your Transcript.

CC: CPIP0404W.2022

Non-Member Price:   $65.00  
Member Price:  $50.00   

2022 CPIP-D Case 4: Transfusion Medicine – Panagglutination: A Blood Bank’s Dilemma