Description
Direct oral anticoagulants (DOACs), such as apixaban and rivaroxaban, arrived on the market with no need for monitoring. As the use of DOACs expand, it is becoming clearer that their measurement may be necessary in specific situations, and more institutions are integrating either qualitative or quantitative assays. To help you stay abreast of current medical thought, use cases and audience polling examples are included to illustrate and prepare for new testing. Additionally, this activity addresses questions such as: Which type of assay is most appropriate for your institution? How do you validate these assays, many of which are not FDA-cleared? When should they be used? How do you integrate the testing in the ordering menu for clinicians?.

This activity was originally presented at CAP23 as part of the activity Optimize or Implement Lab Testing for Xa-Inhibitory Direct Oral Anticoagulant (DOAC) Detection.

Objectives
After completing this activity, you should be able to:

1. Describe indications for measurement of apixaban and rivaroxaban.
2. Describe different types of assays for quantitative or qualitative assessment of these anticoagulants.
3. Approach bringing the appropriate assay for your institution in-house, including validation and integration into the ordering system/electronic medical record.

CME Information
Accreditation: The College of American Pathologists (CAP) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

CME Category 1: The College of American Pathologists designates this internet enduring material educational activity for a maximum of 1 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Payment Information
To pay with a check, print a copy of this page and send it with your check to the address below. You will be notified when your payment has been processed and you have been registered into the activity.

College of American Pathologists
Education Division
325 Waukegan Road
Northfield, IL 60093-2750

Refund Policy
Refunds will be handled on an exception basis. Please submit your request to the CAP in writing via email at education@cap.org or fax at 847-832-8006.

Technical Requirements
Pop-up blockers must be turned off.

CAP Learning has recognized that some Veteran’s Administration, US Government, and military participants may have difficulty accessing the online activity. If you experience difficulty or have any questions, please contact a representative of the Customer Contact Center at 800-323-4040 option 1 or education@cap.org.

Availability
This activity and evaluation are available March 4, 2024, and expire March 3, 2027, at 11:59 PM (CT). Upon completion of the activity your credit will be awarded. Your certificate may be downloaded from your Transcript.

CC: HEMEDOAC03W.2024