Description
Flow cytometry is a powerful diagnostic tool, and is a sensitive method to identify hematolymphoid neoplasms in body fluids and tissues. Some diagnoses in hematopathology are particularly time sensitive, such as acute promyelocytic leukemia. However, there are many other situations in which the oncology team may request a rapid diagnosis, including when patients are very ill, require a specific therapy, or may benefit from enrollment in a clinical trial. Careful evaluation of flow cytometric findings will facilitate interactions with the clinical team and expedite ordering the ancillary tests in a thorough but cost-effective manner. In this activity, case studies are used to explore the strengths (and weaknesses) of flow cytometry in making critical and timely diagnoses. They will discuss the clinical significance of these findings as well as potential pitfalls.

This activity was originally presented at CAP23 as part of the activity Can’t-Miss Diagnoses: Flow Cytometry to Identify Hematolymphoid Neoplasms With Genetic Abnormalities.

Objectives
After completing this activity, you should be able to:

1. Identify “can’t-miss” hematolymphoid neoplasms based on their flow cytometric attributes.
2. Recognize the clinical or prognostic significance of hematolymphoid neoplasms with particular genetic alterations.

CME Information
Accreditation: The College of American Pathologists (CAP) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

CME Category 1: The College of American Pathologists designates this internet enduring material educational activity for a maximum of 1 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Payment Information
To pay with a check, print a copy of this page and send it with your check to the address below. You will be notified when your payment has been processed and you have been registered into the activity.

College of American Pathologists
Education Division
325 Waukegan Road
Northfield, IL 60093-2750

Refund Policy
Refunds will be handled on an exception basis. Please submit your request to the CAP in writing via email at education@cap.org or fax at 847-832-8006.

Technical Requirements
Pop-up blockers must be turned off.

CAP Learning has recognized that some Veteran’s Administration, US Government, and military participants may have difficulty accessing the online activity. If you experience difficulty or have any questions, please contact a representative of the Customer Contact Center at 800-323-4040 option 1 or education@cap.org.

Availability
This activity and evaluation are available March 4, 2024, and expire March 3, 2027, at 11:59 PM (CT). Upon completion of the activity your credit will be awarded. Your certificate may be downloaded from your Transcript.

CC: HEMEFLOC03W.2024