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COPY NUMBER VARIANT SOLID TUMOR - CNVST
CNVST
Analytes/procedures in bold type are regulated for proficiency testing by the Centers for Medicare & Medicaid Services (CMS).

Analyte/Procedure Challenges per Shipment Number of Shipments
Copy number variant—solid tumor 1 Two shipments per year

Additional Information/Minimum Requirements

  • This program is designed for laboratories using next-generation sequencing for copy number analysis.
  • Laboratories will be asked to identify copy number alterations in some of these genes: CDKN2A, CDKN2B, EGFR, ERBB2, FGFR3, MET, MYC, MYCN, TP53.
  • Copy number alterations tested will include amplification, gain, copy neutral loss of heterozygosity, and deletion.

Program Information

  • One 20‑μL gDNA (10 ng/μL) specimen

Shipping Schedule

  • Shipment A: June 14
  • Shipment B: December 13






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