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HISTOQIP IN SITU HYBRIDIZATION - HQISH
HQISH
Analytes/procedures in bold type are regulated for proficiency testing by the Centers for Medicare & Medicaid Services (CMS).

Stain/Tissue Challenges/
Shipment A
Challenges/
Shipment B
Number of Shipments
H&E - Nonneoplastic tonsil 1 Two shipments per year
DNA/RNA positive control probe (ISH) 1
DNA/RNA negative control probe (ISH) 1
Kappa ISH (Kappa probe, ISH) 1
Lambda ISH (Lambda probe, ISH) 1
H&E - Bone marrow core biopsy 1
DNA/RNA positive control probe (ISH) 1
DNA/RNA negative control probe (ISH) 1
Kappa ISH (Kappa probe, ISH) 1
Lambda ISH (Lambda probe, ISH) 1

Additional Information

This program augments efforts to improve the preparation of ISH slides in all anatomic pathology laboratories involved in the handling of specimens undergoing analysis for kappa and lambda expression by chromogenic in situ hybridization.


Program Information

  • Participants are to submit an H&E, positive and negative reagent control slides, and kappa and lambda DNA/RNA ISH stained coverslipped glass slides (one from each category) per mailing

Shipping Schedule

  • Shipment A: January 25
  • Shipment B: June 21

NSH