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MULTIGENE TUMOR PANEL - MTP
Analytes/procedures in bold type are regulated for proficiency testing by the Centers for Medicare & Medicaid Services (CMS).
Challenges per Shipment
Number of Shipments
Two shipments per year
BRAF, EGFR, and KRAS are required analytes. Laboratories that perform testing for the detection of somatic single nucleotide variants, insertions, and deletions in these genes are required to enroll in either MTP or the respective single gene Surveys. This includes laboratories that perform NGS-based assays, non-NGS-based multiplexed assays, and nonmultiplexed assays (eg, Sanger sequencing). Laboratories that perform NGS-based testing are encouraged to also enroll in NGSST, as this proficiency testing program provides challenges with lower variant allele fractions as well as challenges in other genes commonly included in NGS-based panels for the identification of somatic variants in solid tumors.
Three 2.0‑μg gDNA (50ng/‑μL) specimens for laboratories performing molecular testing on multiple targets