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MICROSATELLITE INSTABILITY - MSI
MSI
Analytes/procedures in bold type are regulated for proficiency testing by the Centers for Medicare & Medicaid Services (CMS).

Procedure Challenges per Shipment Number of Shipments
Microsatellite instability testing (DNA amplification) 3 Two shipments per year
MLH1 Promoter methylation analysis 1

Laboratories performing DNA mismatch repair assessment by immunohistochemistry methods should see Survey MMR.


Program Information

  • Two 10.0‑micron unstained paraffin section slides and one H&E slide; two photograph challenges
  • For laboratories performing molecular testing using PCR

Shipping Schedule

  • Shipment A: June 17
  • Shipment B: October 21