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Proficiency Testing/EQA / 2026 Surveys / Genetics and Molecular Pathology /
Cytogenetics

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CAP/ACMG FISH, CONST/HEMAT DISORDERS - CYF
CYF
Analytes/procedures in bold type are regulated for proficiency testing by the Centers for Medicare & Medicaid Services (CMS).

Disease/Procedure Challenges per Shipment Number of Shipments
A B
Constitutional and Hematologic Disorders Two shipments per year
FISH for constitutional disorder - slides 1 1
FISH for constitutional disorder - dry challenge 2 2
FISH for hematologic disorder - slides 1 1
FISH for hematologic disorder - dry challenge 2 2

Additional Information

  • CYF 2026-A:
    Constitutional disorder (two slides) - CEP X
    Hematologic disorder (two slides) - CCND1

  • CYF 2026-B:
    Constitutional disorder (two slides) - 15q11.2 (Prader-Willi/Angelman syndrome critical region)
    Hematologic disorder (two slides) - (CEP7/7q)

  • CYF is prepared from cell suspension samples. For FISH in paraffin-embedded tissues, see programs CYH, CYJ, CYK, CYL, and CYALK.
  • This program is only for laboratories that perform both hybridization and interpretation under the same CLIA number.

Program Information

  • Four slides and four dry challenges

Shipping Schedule

  • Shipment A: April 7
  • Shipment B: August 24






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