Description
Upper and lower endoscopies are commonly performed to evaluate the gastrointestinal (GI) tract in patients with GI symptoms, such as abdominal pain and diarrhea. In patients with GI infections, biopsies are often intensely inflamed or ulcerated. However, some GI infections produce surprisingly little inflammation and can even show nearly normal histologic features. A high level of suspicion is necessary, particularly in specific patient populations, to recognize these infections and order the appropriate ancillary tests to arrive at the correct diagnoses. This activity discusses several GI infections and their risk factors, with an emphasis on those infections that are easily overlooked due to subtle histologic findings, and reviews ancillary techniques to confirm the diagnoses, as appropriate.

This activity was originally presented at CAP24 as part of the activity Hiding in Plain Sight: GI Infections With Minimal Histologic Findings.

Objectives
After completing this activity, you should be able to:

1. Develop a practical approach on how to work up infections in GI biopsies.
2. Recognize GI infections that produce minimal or no inflammatory changes in GI biopsies.
3. Identify the importance that patient population plays in the search for specific infections in the GI tract.

CME Information
Accreditation: The College of American Pathologists (CAP) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

CME Category 1: The College of American Pathologists designates this internet enduring material educational activity for a maximum of 1.5 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Payment Information
To pay with a check, print a copy of this page and send it with your check to the address below. You will be notified when your payment has been processed and you have been registered into the activity.

College of American Pathologists
Education Division
325 Waukegan Road
Northfield, IL 60093-2750

Refund Policy
Refunds will be handled on an exception basis. Please submit your request to the CAP in writing via email at education@cap.org or fax at 847-832-8006.

Technical Requirements
Pop-up blockers must be turned off.

CAP Learning has recognized that some Veteran’s Administration, US Government, and military participants may have difficulty accessing the online activity. If you experience difficulty or have any questions, please contact a representative of the Customer Contact Center at 800-323-4040 option 1 or education@cap.org.

Availability
This activity and evaluation are available March 17, 2025, and expire March 16, 2028, at 11:59 PM (CT). Upon completion of the activity your credit will be awarded. Your certificate may be downloaded from your Transcript.

CC: GIINFECTN03W.2025