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HLA DISEASE ASSOCIATION-DRUG RISK - DADR1
DADR1
Analytes/procedures in bold type are regulated for proficiency testing by the Centers for Medicare & Medicaid Services (CMS).
Analyte
Challenges per Shipment
Number of Shipments
HLA-A*31:01
3
Two shipments per year
HLA-B*13:01
3
HLA-B*15:02
3
HLA-B*57:01
3
HLA-B*58:01
3
Additional Information
This program will challenge the laboratory to accurately identify the presence or absence
of alleles associated with a variety of disease states (listed below) and/or the adverse
reactions to specific drugs.
Carbamazepine-induced Stevens-Johnson syndrome
Allopurinol Stevens-Johnson syndrome
Hypersensitivity to abacavir
Dapsone hypersensitivity
Program Information
Three 0.1‑mL specimens, each containing 200 µg/mL of human DNA in media
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