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MULTIGENE TUMOR PANEL, GEONOMIC DNA - MTP
MTP
Analytes/procedures in bold type are regulated for proficiency testing by the Centers for Medicare & Medicaid Services (CMS).

Analyte Challenges per Shipment Number of Shipments
BRAF 3 Two shipments per year
EGFR 3
ERBB2 (HER2) 3
KIT 3
KRAS 3
NRAS 3
PDGFRA 3
PIK3CA 3

CAP-accredited laboratories that perform testing for the detection of somatic single nucleotide variants, insertions, and deletions in BRAF, EGFR, and KRAS by non-NGS methods are required to enroll in either MTP, or the respective single gene programs. This includes laboratories that perform non-NGS-based multiplexed assays, and nonmultiplexed assays (eg, Sanger sequencing). Laboratories that perform NGS-based testing of somatic single nucleotide variants, insertions, and deletions in BRAF, KRAS, EGFR, and/or other genes are required to enroll in NGSST as this proficiency testing program provides challenges with lower variant allele fractions (VAF) as well as challenges in other genes commonly inlcuded in NGS-based panels for the identification of somatic variants in solid tumors.

Program Information

  • Three 2.0‑μg gDNA (50ng/‑μL) specimens for laboratories performing molecular testing on multiple targets

Shipping Schedule

  • Shipment A: February 8
  • Shipment B: August 16