Developing and Organizing an Institutional Biospecimen Repository - PUB314
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Donna E. Hansel, MD, PhD
Scott D. Jewell, PhD

In recent years, the use of human tissue specimens for research has gained increasing attention, in part because of the intense competition within and outside of academic institutions, ethical issues on ownership, genetic identifiability, and the development of personalized health care. These issues have led to a surge in efforts to define the conditions under which biospecimen repositories are developed and operate.

Developing and Organizing an Institutional Biospecimen Repository provides useful information on establishing and maintaining a biospecimen repository and discusses issues critical to specimen collection, processing, storage, and distribution.

Contents include:

  • Defining the role of the biospecimen repository
  • Developing an institutional resource within the pathology department
  • Management and key personnel
  • Infrastructure of the repository and associated core laboratories
  • Flow of biospecimens to and from the repository
  • Quality control
  • Biorepository informatics
  • Informed consent
  • Cost assessment for developing an institutional biorepository
  • Relationships with outside institutions and industry

Contents (PDF, 70 K)
Sample pages (PDF, 133 K)





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Developing and Organizing an Institutional Biospecimen Repository provides useful information on establishing and maintaining a biospecimen repository (tissue biobank) and discusses issues critical to specimen collection, processing, storage, and distribution. Contents include Defining the role of the biospecimen repository, Developing an institutional resource within the pathology department, Management and key personnel, Infrastructure of the repository and associated core laboratories, Flow of biospecimens to and from the repository, Quality control, Biorepository informatics, Informed consent, Cost assessment for developing an institutional biorepository, Relationships with outside institutions and industry.