The In Vivo Microscopy (IVM) Resource Guide is one of four CAP Resource Guides that bring a collected set of resources together in one place that are focused on a specific hot-topic technology important to pathologists. Each guide highlights current resources, such as a curated set of journal articles, and a collected set of CAP resources that includes learning opportunities, proficiency testing, and accreditation that are related to this technology. Also, each Resource Guide includes an Insights From Adopters section to gain perspective from pathology leaders in the field. This Resource Guide is designed in a modular manner to facilitate its use in several different ways. For example, the guide may be used in its entirety as a comprehensive guide to the rapidly evolving field of IVM. Conversely, it may be used by a pathologist to focus on and gain a current understanding of the application of IVM to a very specific organ system or disease process. Images comparing traditional H&E to IVM images are included in several sections.  The content has been reviewed by experts at the CAP, but does not necessarily reflect the official opinion of the College of American Pathologists.